Ketosis-Prone Diabetes (KPD): case report
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چکیده
منابع مشابه
Ketosis-Prone Diabetes (KPD): case report
Background The ketosis-prone diabetes syndrome (KPD) is characterized by a severe dysfunction of pancreatic beta cells, leading to the diagnosis of diabetic ketoacidosis (DKA) in patients that do not present the typical phenotype of diabetes mellitus type 1 (DM1). This heterogenic condition has been observed more often in urgent care facilities, leading to confusion in diagnosis and potential t...
متن کاملThe ketosis-prone diabetes diagnosis dilemma-a case report
Results A 16-year-old African American male was brought to emergency with abdominal pain, vomiting, lack of appetite and loss of 13kg (regular weight 152Kg, BMI 42.5kg/m). Evaluation detected dehydration, blood glucose of 550mg/dL, acidosis and ketonemia. There was no previous diagnosis of diabetes. He received management for DKA, with fluid therapy and regular insulin via continuous intravenou...
متن کاملKetosis-Onset Diabetes and Ketosis-Prone Diabetes: Same or Not?
Objective. To compare clinical characteristics, immunological markers, and β -cell functions of 4 subgroups ("A β " classification system) of ketosis-onset diabetes and ketosis prone diabetes patients without known diabetes, presenting with ketosis or diabetic ketoacidosis (DKA) and admitted to our department from March 2011 to December 2011 in China, with 50 healthy persons as control group. R...
متن کاملSyndromes of ketosis-prone diabetes mellitus.
Ketosis-prone diabetes (KPD) is a widespread, emerging, heterogeneous syndrome characterized by patients who present with diabetic ketoacidosis or unprovoked ketosis but do not necessarily have the typical phenotype of autoimmune type 1 diabetes. Multiple, severe forms of beta-cell dysfunction appear to underlie the pathophysiology of KPD. Until recently, the syndrome has lacked an accurate, cl...
متن کاملPathogenesis of A−β+ Ketosis-Prone Diabetes
A⁻β⁺ ketosis-prone diabetes (KPD) is an emerging syndrome of obesity, unprovoked ketoacidosis, reversible β-cell dysfunction, and near-normoglycemic remission. We combined metabolomics with targeted kinetic measurements to investigate its pathophysiology. Fasting plasma fatty acids, acylcarnitines, and amino acids were quantified in 20 KPD patients compared with 19 nondiabetic control subjects....
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ژورنال
عنوان ژورنال: Diabetology & Metabolic Syndrome
سال: 2015
ISSN: 1758-5996
DOI: 10.1186/1758-5996-7-s1-a93